Riding close to the Ohio River in the tri-state Kentucky/Indiana/Ohio region, this section moves through the Borderland. This is a narrow strip of land lining both sides of the river that saw some of the Underground Railroad's most intense activity, and where a concentration of physical evidence remaining from those days still exists. The towns of New Albany, Lancaster and Madison in Indiana, and Augusta, Old Washington, and Maysville in Kentucky all have buildings, churches, homes or sites to visit. Roads are generally narrow and winding with low traffic counts. The route alternates between following the river and heading inland. At Maysville you will cross the river into Ohio, and then ride downstream a few miles to Ripley, which comprises a fifty-five acre National Historic District. There is a 16-mile spur into downtown Cincinnati. The city holds numerous sites relating directly to the struggle for freedom, including the National Underground Railroad Freedom Center and the Harriet Beecher Stowe House.

More information about this route is available here.